康龙化成(300759):2023年3月31日投资者关系活动记录表附件之演示文稿(英文版) 焦点速看

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Growth

Performance Business Financial

Strategy

Overview Highlights Highlights

Top 3 YoY:

(RMB mm) 10,266.3

18 Years

+37.9%

Drug discovery service provider

In operation

7,443.8

(2)

globally

5,133.6

3,757.2

20 Locations All Top 20

2,908.1

Global pharmaceutical companies are

Operation sites in China / U.S. / U.K

(1)

our customers

2018mm)32.6%948.1201920202021
Employees (>17,400 scientists &

Gross Profit

Customers served in 2022

(1)

technicians) (RMB mm)

YoY:

37.3% 36.5%

32.6% 35.4% 35.9%

+40.3%

3,749.3

~ 800

~30%

201920202021202217.9%Y:1,834.3 .5%
companies

49.4%

North America,

(3)

(RMB mm)

64.7% Non-listed

Europe(including

36.0%

biopharmaceutical

UK), 14.5%

companies and

19.6%

20.7%

17.9%

Margin 10.8% 14.6% YoY:

Research institutes

1,834.3

+25.5%

China-based customers revenue growth in 2022: 47.5% 1,462.0 1,064.0

Overseas customers revenue growth in 2022:35.9%

549.1

Source: 2019 Annual Report ,2020 Annual Report , 2021 Annual Report, 2022 Annual Report1. As of December 31 ,2022;

313.2

2. By 2020 revenue, Frost & Sullivan analysis;

3. Non-IFRSs net profit for the period excludes the impact from certain expense such as Share-based compensation expenses,

C h i n aU . S . U . K .HoddesdonBeijing HQ Ningbo Campus Ⅰ Beijing TSP Baltimore, MD Germantown, MDLiverpoolDiscovery & Early GLP Safety AssessmentDrug R&D Drug R&D Clinical Research Clinical Bioanalytical CGT CDMO2 Development 2 2 2 21.2 million ft 2.6 million ft 215,000 ft 40,000 ft Sciences, 28,000 ft2103,000 ft2473,000 ftTianjin Shaoxing Xi’an Exton, PA CramlingtonSan Diego, CA RushdenChemical Manufacturing Commercial Manufacturing Chemistry DMPK, CGT Commercial API Mfg.Animal Models, Tox., Ocular Radiolabelled Chem. & 2 2 2 2 22 2538,000 ft 1,791,000 ft 172,000 ft 53,000 ft 60,000 ft (production area)and Medical Devices, 52,000 ft Metabolism, 29,000 ft? According to Frost & Sullivan’s forecast, the global drug R&D and manufacturing spending from 2022 to 2022 will maintain a stable growth, of which, the

pharmaceutical R&D and manufacturing spending in China is expected to grow at a CAGR of 10.7% from 2022 to 2027.

? According to Frost & Sullivan’s forecast, From 2022 to 2027, the outsourcing penetration rate of the global drug R&D and manufacturing spending will further

increase from 2022 to 2027 and the market share of the Chinese drug R&D and manufacturing outsourcing services is expected to reach 25.3% in 2027.

Global Drug R&D and Global Drug R&D and Manufacturing Chinese Drug R&D and Manufacturing Manufacturing Spending Outsourcing Services Market Size Outsourcing Services Market Size (Unit: US $100 million) (Unit: US $100 million)

2027 market share is

8,134

expected 25.3%

RMB 408.7 billion

Forecast

2,675

5,999

CAGR

25.3%

6.3%

Forecast

4,754

CAGR Forecast

+12.3%

11.2%

1,572

CAGR

13.0%

6.0%

CAGR

1,025

CAGR

8.1%

11.3%

+4.9%

2027 2027 2027

2018 2022 2018 2022 2018 2022

Discovery R&D Services Trend CDMO Services Trend Clinical Development Services TrendGlobal discovery CRO China’s discovery R&D Global CDMO services China’s CDMO Global clinical China’s clinical services market size CRO services market market size services market size development services development services size market size market sizeIn 2022-2027 In 2022-2027 In 2022-202748.4%China market share China market share China market share forecast forecast forecast46.7%

1,573

penetration

(Unit: US $100 million)

42.6% rate

359

(Unit: US $100 million)

818

penetration

Forecast

(Unit: US $100 million)

rate

40.8%

CAGR

Forecast

16.0%

CAGR Forecast

penetration

14.8% CAGR

rate

penetration

749 547

8.4%

91

rate

333

180

379

446

CAGR

182

115

13.8%

CAGR

11.8% 32 CAGR

99

9.6% 59

CMC (Small Molecule CDMO) ServicesChemistry development and manufacturing, material science/pre-formulation, formulation development and manufacturing, and analytical development services.Location: China, U.S. and U.K.RevenueRMB 2,406.7 mmGross ProfitRMB 831.7 mmClinical Development ServicesOverseas clinical development services (radiolabeled sciences and clinical trial services) and domestic clinical development services (clinical research services and site management services covering different service needs of clinical research).Location: China, U.S. and U.K.RevenueRMB 1,393.6 mmGross ProfitRMB 159.7 mm
San Diego

Tianjin

2018? Groin37.420709.62019s Profit40.2%18-2022CA956.1202042.6%R: 41.01,378.62021(43.4%YoY g+ 411,980.0
Margin 40.2% 42.6% 43.4% 44.9%

37.4%

Customer

Delivery

Structure

Structure

YoY growth:

2019s Profi27.7%2CAGR: 5249.7202032.6%.2%398.02021(RM34.8%YoY gro+ 36.8608.02022 mm)34.6%th:831.7

Beijing(China)Ningbo(China)GMP intermediates, APITianjin(China)GMP intermediates, APINon GMP Starting Material, IntermediatesShaoxing (China)GMP intermediates, API Non GMP Starting Material, Intermediates Coventry(US)GMP intermediates, APIHoddesdon& Cramlington(UK) GMP intermediates, API
14

Source: 2022 Annual Report. As of December 31, 2022

2019oss Prof25.0%-2022CAGR:113.92020it18.8% 15.9%118.22021(R10.3%YoY grow+62.098.6
? Integrated platform of “radioisotope compound synthesis – clinical – analysis”, established by effectively combining the advantages in radiolabel technology and clinical basis in the UK and US, has been widely Internal and M&A recognized by customers.Expansion

7,393

3D spheroid and organoid models

Biocatalysis

3D spheroid and organoid models

Biocatalysis

CMC

(continuous production technology)

Gene editing technology platform

Ethics and Compliance

ESG Governance

? Business integrity, improve regulatory

? Built a three-tiered ESG governance framework

compliance, 0 legal actions due to

with “governance, management, and

corruption or fraud.

implementation” level

? Information Security

? Issued and implemented the ESG Management

? Ethics of Clinical Trials

Measures and the ESG Information Management

? Animal Welfare

Handbook

? Marketing Compliance

? Developed the 2021-2025 environmental targets

? Issue the first standalone ESG Report

Environmentally Sustainable

and Low-Carbon Operations

Responsible Operations

? High-quality products

? Responding to Climate Change

? Innovative technologies

? Sustainable Environmental Goals

? Quality Services

? Environmental Management

? Stable and sustainable supply

chain

? Pollution Prevention and Control

? Resource Protection

Empowering Talent Development

Green and Low-Carbon Operations2021-2025 Environmental Targets2022 MSCI ESG:BBB/per RMB10,000 of output value

Achieved a “B” scoring for CPD Climate Change

? The Company has been ISO14001-certified.

? Joined the ACS GCI2 Pharmaceutical Roundtable.

water Energy CO2

? Received a Gold certification from the My Green

consumption consumption emissions

Lab.

Reduce 10% Reduce 10% Reduce 10%

Maintaining 100% compliance in waste

In the 12th China Securities Golden Bauhinia Awards,

? Included in HSCI, HSHCI, MSCI China Health Care Index, CHINEXT Composite, SZSE Component IndexInfluential Enterprise of Top 50 Valuable Eighth of the “Top Best ESG Practice the Year” awarded on Listed Companies on 25 Pharmaceutical Listed CompanyCCV Award CeremonyGEMCompanies” Revenue

RMB mm

Revenue

RMB mm

Biologics and CGT Services

87.9%

Other

2021RMB mmGross PMargin35.92,672.0 20212022ofit and Margin36.5oY growth3,749.3 40.3%
Non-IFRSs net profit attributable to

Gross Profit and Margin (1)

RMB mm

Net Profit and Margin

(2)

owners of the company

Margin

35.9% 36.5% Margin 22.3% 13.4% Margin 19.6% 17.9%

YoY growth

3,749.3

YoY growth

YoY growth

1,661.0

YoY growth

+40.3%

+4.1%

+25.5%

-17.2% 1,834.3

2,672.0

2,058.0

2,142.8

1,374.6

1,462.0

20212022
RMB mm 2021 2022

17.9%

19.6%

Margin

Profit attributable to owners of the parent

1,661.0 1,374.6

1,834.3

Add:

YoY growth

Share-based compensation expenses

56.8 157.2 +25.5%

1,462.0

Convertible Bonds related (gains)/losses

(12.9) 142.0

Foreign exchange related (gains)/losses

(23.4) 77.7

Realized and unrealized (gains)/losses

from equity investments

(219.5) 82.8

Non-IFRS adjusted net profit attributable

to owners of the parent

20212022
Both revenue and non-IFRSs net profit of the established business segments excluding impact from Biologics and CGT Services and the addition of overseas small

molecule manufacturing capacities achieved solid growth in the first 9 months of 2022.? Biologics and CGT Services - Since 2021, we began to build our Biologics and CGT Services through internal buildup and external acquisitions for the medium and

long-term growth of the company. As these new business are still in the integration and investment stage, there are certain negative impact on the profitability in 2022.

? Addition of overseas small molecule manufacturing capacities - Since 2022, with the strategy of establishing a global service network for the small molecule CDMO

services, we have acquired manufacturing sites in UK and US in January and July 2022, respectively. As we are in the process of integrating these manufacturing

capacities into our services platform, there are certain negative impact on the profitability in 2022.

Non-IFRSs net profit attributable to

Revenue

owners of the company

RMBmm

RMBmm

10,266.3 1
10,018.2
1,834.3
7,443.8
7,292.8
1,560.3
1,462.0

? Administrative expenses as % of Total Revenue: During the reporting period, the Company completed several overseas acquisitions.

With the relatively low revenue in the integration stage, the administrative expenses as % of total revenue increased.

(1)

Administrative expenses as % of Total Revenue

Selling and distribution expenses as % of Total Revenue

? Administrative expenses as % of Total Revenue: During the reporting period, the Company completed several overseas acquisitions.

With the relatively low revenue in the integration stage, the administrative expenses as % of total revenue increased.

(1)

Administrative expenses as % of Total Revenue

Selling and distribution expenses as % of Total Revenue

14.5%

13.7%

13.4%

12.1%

11.3%

2.2%

2.1%

1.9% 1.9%

1.8%

2018Researc1.1%2019 and Devel1.7%2020pment Cos2.1%2021t as % of T2022tal Revenu

201820192020(2.1)%2021(1.2)%2022
20182019202020212022
(2)

(1)

Trade Payables Turnover

Trade Receivables and Contract Assets Turnover

(2)

(1)

Trade Payables Turnover

Trade Receivables and Contract Assets Turnover

Days

Days

78.5

77.7

19.9

75.2

19.1

18.4

65.6 65.6 17.3

16.8

2018Days11.92019Inven12.42020tories Turn12.62021(2)ver2022
2018Days7.82019Contr8.22020act Costs T11.92021(2)rnover2022
Days

Days

15.0

12.0

11.9

12.6

12.4

11.9

11.7

9.6

8.2

7.8

20182019202020212022
20182019202020212022
note

Capital Expenditure

Bank-related Assets, Bank Facilities and Loans

note

Capital Expenditure

Bank-related Assets, Bank Facilities and Loans

RMB mm RMB mm

9,115.7

754.6

641.0

1,434.0

844.4

781.0

217.7 560.8

2018BSCnk--Baonveelatk Lrtobl2019d Aanse Bosetsnds2020UnLT-tilisBan2021d B LoankinnsFa2022ilitie
Internal Construction Equity Investments

ST-Bank Loans LT-Bank Loans

Convertoble Bonds

? Continue to build and improve our “end-to-end, fully integrated and global” pharmaceutical R&D service platform

Strengthen the leading position in the

Continue to strengthen the fully

Continue accelerating the build-up of

small molecule R&D service area

integrated clinical development services

biologics and CGT services platform

platform

Continue to strengthen our talent

Further enhance management

pool to support our long-term

capabilities

and sustainable growth

Continue to expand domestic

and overseas market shares

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